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APOL1-IN-1

CAS No. 2446817-72-5

APOL1-IN-1( —— )

Catalog No. M35181 CAS No. 2446817-72-5

APOL1-IN-1 is a potent inhibitor of apolipoprotein L1 (APOL1) that can be used to study the pathogenesis of focal segmental glomerulosclerosis (FSGS) and nondiabetic kidney disease (NDKD), facilitating research into these diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 188 In Stock
5MG 235 In Stock
10MG 377 In Stock
25MG 776 In Stock
50MG 1200 In Stock
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Biological Information

  • Product Name
    APOL1-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    APOL1-IN-1 is a potent inhibitor of apolipoprotein L1 (APOL1) that can be used to study the pathogenesis of focal segmental glomerulosclerosis (FSGS) and nondiabetic kidney disease (NDKD), facilitating research into these diseases.
  • Description
    APOL1-IN-1 is a apolipoprotein L1 (APOL1) inhibitor extracted from patent WO2020131807A1 compound 87. APOL1-IN-1 can be used for the research of focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2446817-72-5
  • Formula Weight
    381.4
  • Molecular Formula
    C21H20FN3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (327.74 mM; Ultrasonic )
  • SMILES
    O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2ccccc12)-c1ccc(F)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brodney M, et, al. Inhibitors of apol1 and methods of using same. WO2020131807A1.
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