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NF-κΒ activator 1
CAS No. 2387524-59-4
NF-κΒ activator 1( —— )
Catalog No. M35172 CAS No. 2387524-59-4
NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 223 | In Stock |
|
| 5MG | 202 | In Stock |
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| 10MG | 330 | In Stock |
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| 25MG | 560 | In Stock |
|
| 50MG | 783 | In Stock |
|
| 100MG | 1079 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2167 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNF-κΒ activator 1
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NoteResearch use only, not for human use.
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Brief DescriptionNF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.
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DescriptionNF-κΒ activator 1 is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD)2 mRNA expression.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetNF-κB
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RecptorNF-κB
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Research Area——
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Indication——
Chemical Information
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CAS Number2387524-59-4
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Formula Weight314.33
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Molecular FormulaC16H11FN2O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (318.14 mM; Ultrasonic )
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SMILESOC(=O)c1cccc(c1)-c1csc(Nc2ccccc2F)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-?B activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952.?
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