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Home - Products - Metabolic Enzyme/Protease - Phosphatase - JAB-3068

JAB-3068

CAS No. 2169223-48-5

JAB-3068( —— )

Catalog No. M35136 CAS No. 2169223-48-5

JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor exhibiting anticancer and antitumor properties, designed for research in breast, lung, and esophageal cancers.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 359 In Stock
50MG 529 In Stock
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Biological Information

  • Product Name
    JAB-3068
  • Note
    Research use only, not for human use.
  • Brief Description
    JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor exhibiting anticancer and antitumor properties, designed for research in breast, lung, and esophageal cancers.
  • Description
    JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC50 of 25.8 nM.
  • In Vitro
    JAB-3068 (SHP2-IN-6) inhibits the proliferation of KYSE-520 cells with an IC50 of 2.17 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Phosphatase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2169223-48-5
  • Formula Weight
    476.54
  • Molecular Formula
    C22H26F2N6O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    S(C1=C2C(N(C(C)=O)CC2(F)F)=CC=C1)C=3C(N)=NC(=CN3)N4CCC5(CC4)[C@H](N)COC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cunbo Ma, et al. Novel heterocyclic derivatives useful as shp2 inhibitors. WO2017211303A1.
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