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Disitamab vedotin
CAS No. 2136633-23-1
Disitamab vedotin( —— )
Catalog No. M35132 CAS No. 2136633-23-1
Disitamab vedotin (RC-48) is a newly developed antibody-active molecule conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2), consisting of hertuzumab coupled to monomethyl auristatin E (MMAE) via a cleavable linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 796 | In Stock |
|
| 10MG | 1102 | In Stock |
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| 25MG | 1634 | In Stock |
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| 50MG | 2158 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDisitamab vedotin
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NoteResearch use only, not for human use.
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Brief DescriptionDisitamab vedotin (RC-48) is a newly developed antibody-active molecule conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2), consisting of hertuzumab coupled to monomethyl auristatin E (MMAE) via a cleavable linker.
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DescriptionDisitamab vedotin (RC48) is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against human epidermal growth factor receptor 2 (HER2) conjugated via a cleavable linker to the cytotoxic agent Monomethyl auristatin E (MMAE). Disitamab vedotin enhances antitumor immunity.
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In VitroThe antibody part was a humanized monoclonal antibody targeting HER2, the small molecule toxin was monomethyl auristatin E (MMAE), a synthetic antineoplastic agent. A protease cleavable linker covalently attached MMAE to the antibody.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorAntibody-Drug Conjugates (ADCs) | EGFR
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Research Area——
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Indication——
Chemical Information
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CAS Number2136633-23-1
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Formula WeightApproximately 144.15 kDa
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Deeks ED. Disitamab Vedotin: First Approval. Drugs. 2021;81(16):1929-1935.?
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