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TPh A
CAS No. 21306-65-0
TPh A( —— )
Catalog No. M35129 CAS No. 21306-65-0
TPh A (Triphenyl Compound A) is an inhibitor of the nuclear protein pirin (Ki: 0.6 uM), a protein that can be used as a bioprobe to regulate pirin-related functions.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 74 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameTPh A
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NoteResearch use only, not for human use.
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Brief DescriptionTPh A (Triphenyl Compound A) is an inhibitor of the nuclear protein pirin (Ki: 0.6 uM), a protein that can be used as a bioprobe to regulate pirin-related functions.
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DescriptionTPh A (Triphenyl Compound A) is a potent inhibitor of the nuclear protein pirin and binds specifically to pirin with a Ki of 0.6 uM. TPh A disrupts the formation of the bcl3–pirin complex. TPh A can be used as a novel small molecule tool to regulate pirin in cells.
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In VitroCell Viability Assay Cell Line:MCF7, MDA-MB231, HeLa, DU145, HepG2, A549, HT1080, WM266-4, and SK-MEL-28 cells Concentration:0-100 μM Incubation Time:48 hours Result:Did not exert any potent cytotoxic activity against many human cancer cell lines.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number21306-65-0
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Formula Weight399.53
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Molecular FormulaC21H21NO3S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (625.74 mM; Ultrasonic )
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SMILESCc1ccc(cc1)S(=O)(=O)\N=S(/C)c1ccc(OCc2ccccc2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Isao Miyazaki, et al. A Small-Molecule Inhibitor Shows That Pirin Regulates Migration of Melanoma Cells. Nat Chem Biol. 2010 Sep;6(9):667-73.?
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