NS-102

CAS No. 136623-01-3

NS-102( —— )

Catalog No. M35069 CAS No. 136623-01-3

NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2), which reduces glur6 receptor-mediated currents, and inhibits specific binding to the glur6 receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 376 In Stock
10MG 629 In Stock
25MG 1036 In Stock
50MG 1367 In Stock
100MG 1841 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    NS-102
  • Note
    Research use only, not for human use.
  • Brief Description
    NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2), which reduces glur6 receptor-mediated currents, and inhibits specific binding to the glur6 receptor.
  • Description
    NS-102 is a selective kainate (GluK2) receptor antagonist. NS-102 is a potent GluR6/7 receptor antagonist.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Neuroscience
  • Target
    GluR
  • Recptor
    GluR | NMDAR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    136623-01-3
  • Formula Weight
    261.23
  • Molecular Formula
    C12H11N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 4 mg/mL (15.31 mM; Ultrasonic (<60°C)
  • SMILES
    O\N=C1/C(=O)Nc2c1cc(c1CCCCc21)[N+]([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Selva Baltan Tekk?k, et al. Excitotoxic mechanisms of ischemic injury in myelinated white matter. J Cereb Blood Flow Metab. 2007 Sep;27(9):1540-52.?
molnova catalog
related products
  • MNI 137

    MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.

  • LY404187

    LY404187 is a positive allosteric modulator of AMPA receptors.

  • S-(4-Hydroxybenzyl)g...

    L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.