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CAY10640
CAS No. 1208549-68-1
CAY10640( —— )
Catalog No. M35030 CAS No. 1208549-68-1
CAY10640 (sEH inhibitor-1) is a potent, orally active, water-soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in humans and mice with IC50s of 0.4 and 5.3 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 271 | Get Quote |
|
| 5MG | 423 | Get Quote |
|
| 10MG | 623 | Get Quote |
|
| 25MG | 908 | Get Quote |
|
| 50MG | 1288 | Get Quote |
|
| 100MG | 1692 | Get Quote |
|
| 500MG | 3402 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCAY10640
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NoteResearch use only, not for human use.
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Brief DescriptionCAY10640 (sEH inhibitor-1) is a potent, orally active, water-soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in humans and mice with IC50s of 0.4 and 5.3 nM, respectively.
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DescriptionsEH inhibitor-1 (compound TCPU ) is a potent and oral active inhibitor of sEH (soluble epoxide hydrolase) with IC50s of 0.4 and 5.3 nM in human and murine, respectively.
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In Vitro——
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In VivoPharmacokinetic parameters of sEH inhibitor-1 (TCPU) after oral gavage with a non-compartmental analysis.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorEpoxide Hydrolase
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Research Area——
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Indication——
Chemical Information
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CAS Number1208549-68-1
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Formula Weight371.35
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Molecular FormulaC17H20F3N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (336.61 mM; Ultrasonic )
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SMILESC(=O)(C1CC1)N2CCC(NC(NC3=CC=C(OC(F)(F)F)C=C3)=O)CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Liu JY, et al. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. Eur J Pharm Sci. 2013;48(4-5):619-627. ?
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