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Stearoyl-L-carnitine chloride

CAS No. 32350-57-5

Stearoyl-L-carnitine chloride( —— )

Catalog No. M34977 CAS No. 32350-57-5

Stearoyl-L-carnitine chloride (Acylcarnitine C18:0) is a long-chain acylcarnitine found in the cerebellum that inhibits GlyT2 and is an important component in the study of lipid metabolism.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Stearoyl-L-carnitine chloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Stearoyl-L-carnitine chloride (Acylcarnitine C18:0) is a long-chain acylcarnitine found in the cerebellum that inhibits GlyT2 and is an important component in the study of lipid metabolism.
  • Description
    Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM.
  • In Vitro
    Stearoyl-L-carnitine (0.01-10 μM) inhibits glycine (30 μM) transports by 16.8% at concentrations up 3 μM in Xenopus laevis oocytes.Stearoyl-L-carnitine (500 μM; 30 min) inhibits Na+-dependent [3H]carnitine (20 nM) uptake by ~50% in HPCT cells.
  • In Vivo
    Stearoyl-L-carnitine is significantly decreased in Alzheimer's disease (AD), mild cognitive impairment (MCI) and subjective memory complaint (SMC).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    32350-57-5
  • Formula Weight
    464.12
  • Molecular Formula
    C25H50ClNO4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [Cl-].CCCCCCCCCCCCCCCCCC(=O)O[C@H](CC(O)=O)C[N+](C)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cristofano A, et, al. Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia. PLoS One. 2016 May 19;11(5):e0155694.?
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