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Endosidin-2
CAS No. 1839524-44-5
Endosidin-2( —— )
Catalog No. M34902 CAS No. 1839524-44-5
Endosidin-2 is an exocyst inhibitor, a cell-permeable benzylidene benzoylhydrazine, that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 μM, EXO70A1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 49 | In Stock |
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| 5MG | 45 | In Stock |
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| 10MG | 85 | In Stock |
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| 25MG | 187 | In Stock |
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| 50MG | 299 | In Stock |
|
| 100MG | 500 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1070 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEndosidin-2
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NoteResearch use only, not for human use.
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Brief DescriptionEndosidin-2 is an exocyst inhibitor, a cell-permeable benzylidene benzoylhydrazine, that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 μM, EXO70A1).
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DescriptionEndosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1839524-44-5
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Formula Weight414.17
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Molecular FormulaC15H12FIN2O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (241.45 mM; Ultrasonic )
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SMILESCOC1=CC(\C=N\NC(=O)C2=CC=CC(F)=C2)=CC(I)=C1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang C, et al. Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E41-50. ?
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