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ML 315

CAS No. 1440251-53-5

ML 315( —— )

Catalog No. M34876 CAS No. 1440251-53-5

ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 93 In Stock
10MG 155 In Stock
25MG 330 In Stock
50MG 529 In Stock
100MG 756 In Stock
200MG Get Quote In Stock
500MG 1516 In Stock
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Biological Information

  • Product Name
    ML 315
  • Note
    Research use only, not for human use.
  • Brief Description
    ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.
  • Description
    ML 315 is a selective dual inhibitor of CDK and DYRK with IC50s of 68 nM and 282 nM, respectively. ML 315 is used in cancer and neurological disease research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DYRK | CDK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1440251-53-5
  • Formula Weight
    374.22
  • Molecular Formula
    C18H13Cl2N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ClC=1C=C(Cl)C=C(C1)CNC=2N=CN=CC2C3=CC=C4OCOC4=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Coombs TC, et al. Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3654-61.?
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