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KR-32568
CAS No. 852146-73-7
KR-32568( —— )
Catalog No. M34859 CAS No. 852146-73-7
KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM) with potent cardioprotective effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 83 | In Stock |
|
| 5MG | 88 | In Stock |
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| 10MG | 141 | In Stock |
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| 25MG | 283 | In Stock |
|
| 50MG | 403 | In Stock |
|
| 100MG | 551 | In Stock |
|
| 200MG | 728 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKR-32568
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NoteResearch use only, not for human use.
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Brief DescriptionKR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM) with potent cardioprotective effects.
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DescriptionKR-32568 is a sodium/hydrogen exchanger-1 (NHE-1) inhibitor with an IC50 of 230 nM. KR-32568 has cardioprotective effects.
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In Vitro——
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In VivoAnimal Model:Male Sprague-Dawley rats (350-380 g) bearing 30 min ischemia/2.5 h reperfusion heart injury Dosage:0.1 mg/kg and 1.0 mg/kg Administration:i.v.; once Result:Exerted potent cardioprotective effects in rats.
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorSodium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number852146-73-7
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Formula Weight261.25
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Molecular FormulaC13H12FN3O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (382.78 mM; Ultrasonic )
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SMILESCC1=C(C=2OC(C(NC(=N)N)=O)=CC2)C=C(F)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hui-Yul Roh, et al. Cardioprotective effects of [5-(2-methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32568) in an anesthetized rat model of ischemia and reperfusion heart injury. Pharmacology. 2005 Dec;75(1):37-44. ?
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