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Izencitinib

CAS No. 2051918-33-1

Izencitinib( —— )

Catalog No. M34800 CAS No. 2051918-33-1

Izencitinib (JNJ-8398) is an orally active and gut-selective JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	206	In Stock
5MG	187	In Stock
10MG	297	In Stock
25MG	598	In Stock
50MG	918	In Stock
100MG	1479	In Stock
200MG	2027	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Izencitinib
Note

Research use only, not for human use.
Brief Description

Izencitinib (JNJ-8398) is an orally active and gut-selective JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.
Description

Izencitinib (TD-1473) is an orally active, non-selective and gut-restricted JAK inhibitor. Izencitinib (TD-1473) can be used in the study for ulcerative colitis.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

JAK
Recptor

JAK
Research Area

——
Indication

——

Chemical Information

CAS Number

2051918-33-1
Formula Weight

402.5
Molecular Formula

C22H26N8
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (124.22 mM; Ultrasonic )
SMILES

Cc1cc(Nc2cc3ncccc3c(N[C@H]3C[C@@H]4CC[C@H](C3)N4CCC#N)n2)n[nH]1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kevin S Currie, et al. Small-molecule agents for the treatment of inflammatory bowel disease. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2034-2041.?

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