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CTA 056

CAS No. 1265822-30-7

CTA 056( —— )

Catalog No. M34772 CAS No. 1265822-30-7

CTA 056 is an interleukin-2 induced T cell kinase (ITK) inhibitor, inhibits the growth of MOLT-4 xenograft tumors in mice, induces apoptosis in Jurkat cells, and can be used in the study of autoimmune disorders and T cell malignancies.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    CTA 056
  • Note
    Research use only, not for human use.
  • Brief Description
    CTA 056 is an interleukin-2 induced T cell kinase (ITK) inhibitor, inhibits the growth of MOLT-4 xenograft tumors in mice, induces apoptosis in Jurkat cells, and can be used in the study of autoimmune disorders and T cell malignancies.
  • Description
    CTA056 is an ITK (IL-2-inducible T-cell kinase) inhibitor with an IC50 of 0.1 μM. CTA056 selectively targets malignant T cells and modulates oncomirs. CTA056 induces apoptosis and is a potential therapeutic agent for the research of T-cell leukemia and lymphoma.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1265822-30-7
  • Formula Weight
    554.68
  • Molecular Formula
    C35H34N6O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1NC=2C=C3N=C(C=4C=CC(=CC4)C=5C=CN=CC5)N(C3=CC2N=C1CC=6C=CC=CC6)CCCN7CCCCC7
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Guo W, et al. Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Mol Pharmacol. 2012 Nov;82(5):938-47.?
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