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ST-1006

CAS No. 1196994-11-2

ST-1006( —— )

Catalog No. M34715 CAS No. 1196994-11-2

ST-1006, a potent histamine H4 receptor agonist (pKi: 7.94), exhibits significant anti-inflammatory and anti-pruritic effects. It is also a potent inducer of basophil migration.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 198 In Stock
5MG 199 In Stock
10MG 316 In Stock
25MG 514 In Stock
50MG 620 In Stock
100MG 768 In Stock
200MG 1023 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    ST-1006
  • Note
    Research use only, not for human use.
  • Brief Description
    ST-1006, a potent histamine H4 receptor agonist (pKi: 7.94), exhibits significant anti-inflammatory and anti-pruritic effects. It is also a potent inducer of basophil migration.
  • Description
    ST-1006 is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 has anti-inflammatory effect.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male CD-1 mice with pruritus (8-10 weeks and 25-30 g)Dosage:1-100 mg/kg Administration:Subcutaneous injection Result:Had an antipruritic effect at the non-anti-inflammatory dose of 30 mg/kg.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    Histamine Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1196994-11-2
  • Formula Weight
    367.28
  • Molecular Formula
    C16H20Cl2N6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(CC1=C(Cl)C=CC=C1Cl)C2=CC(N3CCN(C)CC3)=NC(N)=N2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Adami M, et, al. Differential effects of functionally different histamine H4 receptor ligands on acute irritant dermatitis in mice. Naunyn Schmiedebergs Arch Pharmacol. 2018 Dec;391(12):1387-1397.?
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