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ST-1006
CAS No. 1196994-11-2
ST-1006( —— )
Catalog No. M34715 CAS No. 1196994-11-2
ST-1006, a potent histamine H4 receptor agonist (pKi: 7.94), exhibits significant anti-inflammatory and anti-pruritic effects. It is also a potent inducer of basophil migration.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 198 | In Stock |
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| 5MG | 199 | In Stock |
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| 10MG | 316 | In Stock |
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| 25MG | 514 | In Stock |
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| 50MG | 620 | In Stock |
|
| 100MG | 768 | In Stock |
|
| 200MG | 1023 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameST-1006
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NoteResearch use only, not for human use.
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Brief DescriptionST-1006, a potent histamine H4 receptor agonist (pKi: 7.94), exhibits significant anti-inflammatory and anti-pruritic effects. It is also a potent inducer of basophil migration.
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DescriptionST-1006 is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 has anti-inflammatory effect.
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In Vitro——
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In VivoAnimal Model:Male CD-1 mice with pruritus (8-10 weeks and 25-30 g)Dosage:1-100 mg/kg Administration:Subcutaneous injection Result:Had an antipruritic effect at the non-anti-inflammatory dose of 30 mg/kg.
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Synonyms——
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorHistamine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1196994-11-2
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Formula Weight367.28
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Molecular FormulaC16H20Cl2N6
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Purity>98% (HPLC)
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Solubility——
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SMILESN(CC1=C(Cl)C=CC=C1Cl)C2=CC(N3CCN(C)CC3)=NC(N)=N2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Adami M, et, al. Differential effects of functionally different histamine H4 receptor ligands on acute irritant dermatitis in mice. Naunyn Schmiedebergs Arch Pharmacol. 2018 Dec;391(12):1387-1397.?
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