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Giripladib
CAS No. 865200-20-0
Giripladib( —— )
Catalog No. M34608 CAS No. 865200-20-0
Giripladib (PLA695)(PLX-695) is a cPLA2-specific inhibitor that inhibits the radiation-induced increase of phosphorylated ERK and phosphorylated Akt in endothelial cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 623 | In Stock |
|
| 5MG | 426 | In Stock |
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| 10MG | 625 | In Stock |
|
| 25MG | 938 | In Stock |
|
| 50MG | 1283 | In Stock |
|
| 100MG | 1758 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGiripladib
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NoteResearch use only, not for human use.
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Brief DescriptionGiripladib (PLA695)(PLX-695) is a cPLA2-specific inhibitor that inhibits the radiation-induced increase of phosphorylated ERK and phosphorylated Akt in endothelial cells.
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DescriptionGiripladib (PLA-695) is a indole-based inhibitor of cytosolic phospholipase A2 (cPLA2). Giripladib can be used for osteoarthritis and breast cancer research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhospholipase
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RecptorPhospholipase
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Research Area——
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Indication——
Chemical Information
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CAS Number865200-20-0
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Formula Weight745.25
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Molecular FormulaC41H36ClF3N2O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESC(N1C(CCNS(CC2=C(C(F)(F)F)C=CC=C2)(=O)=O)=C(CCCC3=CC=C(C(O)=O)C=C3)C=4C1=CC=C(Cl)C4)(C5=CC=CC=C5)C6=CC=CC=C6
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kokotos G, et al. Inhibition of group IVA cytosolic phospholipase A2 by thiazolyl ketones in vitro, ex vivo, and in vivo. J Med Chem. 2014 Sep 25;57(18):7523-35.?
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