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Clerodendrin

CAS No. 119738-57-7

Clerodendrin( —— )

Catalog No. M34549 CAS No. 119738-57-7

Clerodendrin (Apigenin-7-O-glucuronopyranosyl(1-2)-glucuronopyranoside) is a new neodentate diterpenoid isolated from the leaves of Clerodendron trichotomm, a radish sawfly Athalia Clerodendrin is an interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Clerodendrin
  • Note
    Research use only, not for human use.
  • Brief Description
    Clerodendrin (Apigenin-7-O-glucuronopyranosyl(1-2)-glucuronopyranoside) is a new neodentate diterpenoid isolated from the leaves of Clerodendron trichotomm, a radish sawfly Athalia Clerodendrin is an interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor.
  • Description
    Clerodendrin is a nature product could be isolated from Lobelia chinensis. Clerodendrin is a potent dual Interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor.
  • In Vitro
    Clerodendrin (10 μM; 1 and 3 h) inhibits IL-4 mRNA expression and the release of β-hexosaminidase in Propidium Iodide (HY-D0815)-induced RBL-2H3 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Interleukin | IL Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    119738-57-7
  • Formula Weight
    622.49
  • Molecular Formula
    C27H26O17
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (80.32 mM; Ultrasonic )
  • SMILES
    O=C1C=2C(OC(=C1)C3=CC=C(O)C=C3)=CC(O[C@H]4[C@H](O[C@@H]5O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O4)=CC2O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Young KT, et, al. Inhibition of Interleukin-4 and β-Hexosaminidase Release in RBL-2H3 Cells by Compounds Isolated from Lobelia chinensis. 2021,27(4):251-6.
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