Cart
sales@molnova.com
AZD1940
CAS No. 881413-29-2
AZD1940( —— )
Catalog No. M34518 CAS No. 881413-29-2
AZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 201 | Get Quote |
|
| 5MG | 312 | Get Quote |
|
| 10MG | 535 | Get Quote |
|
| 25MG | 820 | Get Quote |
|
| 50MG | 1132 | Get Quote |
|
| 100MG | 1503 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAZD1940
-
NoteResearch use only, not for human use.
-
Brief DescriptionAZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.
-
DescriptionAZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pKi values of 7.93 and 9.06 for human CB1R and CB2R, respectively. AZD1940 shows a robust analgesia action.
-
In VitroAZD1940 binds with high affinity to human, rat and mouse CB1 and CB2 receptors and displays full agonism at both receptors in all three species.
-
In VivoWhen given orally to rats, AZD1940 produces a robust analgesia in different models of inflammatory and neuropathic pain.For AZD1940, low brain uptake at analgesic doses has been demonstrated in both rats and primates.
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetCannabinoid Receptor
-
RecptorCannabinoid Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number881413-29-2
-
Formula Weight413.52
-
Molecular FormulaC20H29F2N3O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (241.83 mM; Ultrasonic )
-
SMILESCCS(=O)(=O)Nc1ccc2n(CC3CCC(F)(F)CC3)c(nc2c1)C(C)(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jarkko Kalliom?ki, et al. Evaluation of the analgesic efficacy and psychoactive effects of AZD1940, a novel peripherally acting cannabinoid agonist, in human capsaicin-induced pain and hyperalgesia. Clin Exp Pharmacol Physiol. 2013 Mar;40(3):212-8.?
molnova catalog
related products
-
Revosimeline
A novel potent cannabinoid receptor agonist.
-
CB2R/FAAH?modulator-...
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting CB2R and FAAH, acting as a CB2R agonist (Ki = 10.8 nM) and FAAH inhibitor (IC50 = 6.2 μM), with a Ki value of 152.9 nM for CB1R.
-
SMM-295
A novel potent, selective cannabinoid receptor 2 (CB2) agonist with Ki of 12 nM.
