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PGP-4008
CAS No. 365565-02-2
PGP-4008( —— )
Catalog No. M34378 CAS No. 365565-02-2
PGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration with Doxorubicin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 37 | In Stock |
|
| 5MG | 65 | In Stock |
|
| 10MG | 105 | In Stock |
|
| 25MG | 199 | In Stock |
|
| 50MG | 308 | In Stock |
|
| 100MG | 461 | In Stock |
|
| 200MG | 624 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePGP-4008
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NoteResearch use only, not for human use.
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Brief DescriptionPGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration with Doxorubicin.
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DescriptionPGP-4008 is a specific P-glycoprotein (Pgp) inhibitor. PGP-4008 inhibits tumor growth in a murine syngeneic Pgp-mediated multiple agent resistance (MDR) solid tumor model when given in combination with Doxorubicin.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorP-gp
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Research Area——
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Indication——
Chemical Information
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CAS Number365565-02-2
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Formula Weight393.48
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Molecular FormulaC26H23N3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (158.84 mM; Ultrasonic (<60°C)
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SMILESO=C(Cc1ccccc1)Nc1c2CCN(Cc3ccccc3)c2nc2ccccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Brian D Lee, et al. Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem. 2004 Mar 11;47(6):1413-22.?
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