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LSN2463359

CAS No. 1401031-52-4

LSN2463359( —— )

Catalog No. M34321 CAS No. 1401031-52-4

LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 73 Get Quote
25MG 159 Get Quote
50MG 251 Get Quote
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Biological Information

  • Product Name
    LSN2463359
  • Note
    Research use only, not for human use.
  • Brief Description
    LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.
  • Description
    LSN2463359 is positive allosteric modulator of metabotropic glutamate 5 (mGlu5). LSN2463359 attenuates aspects of the behavioral response to administration of the competitive NMDA receptor antagonist. LSN2463359 selectively attenuates reversal learning deficits observed in the neurodevelopmental MAM E17 model. LSN2463359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Neuroscience
  • Target
    GluR
  • Recptor
    GluR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1401031-52-4
  • Formula Weight
    265.31
  • Molecular Formula
    C16H15N3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (471.15 mM; Ultrasonic )
  • SMILES
    CC(C)NC(=O)c1ccc(cn1)C#Cc1ccncc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gastambide F, et al. The mGlu? positive allosteric modulator LSN2463359 differentially modulates motor, instrumental and cognitive effects of NMDA receptor antagonists in the rat. Neuropharmacology. 2013;64:240-247.?
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