GPRP
CAS No. 67869-62-9
GPRP( —— )
Catalog No. M34267 CAS No. 67869-62-9
GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein IIb/IIIa complex (glycoprotein IIb/IIIa receptor).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameGPRP
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NoteResearch use only, not for human use.
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Brief DescriptionGPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein IIb/IIIa complex (glycoprotein IIb/IIIa receptor).
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DescriptionGPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorIntegrin
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Research Area——
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Indication——
Chemical Information
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CAS Number67869-62-9
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Formula Weight425.48
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Molecular FormulaC18H31N7O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : ≥ 50 mg/mL (117.51 mM)DMSO : 20.83 mg/mL (48.96 mM; Ultrasonic )
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SMILESC([C@@H](NC(=O)[C@H]1N(C(CN)=O)CCC1)CCCNC(=N)N)(=O)N2[C@H](C(O)=O)CCC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Roxifiban acetate
Roxifiban acetate(DMP 754 acetate) is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used in the study of human thrombocytopenia.
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Lifitegrast sodium
Lifitegrast sodium (SAR-1118-023 sodium) is a small molecule integrin antagonist that inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), which reduces inflammation of the ocular surface, and may be used in the study of dry eye.
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αvβ1 integrin-IN-1
αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.
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