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3α,21-Dihydroxy-5α-pregnan-20-one
CAS No. 567-02-2
3α,21-Dihydroxy-5α-pregnan-20-one( —— )
Catalog No. M34145 CAS No. 567-02-2
3α,21-Dihydroxy-5α-pregnan-20-one (5alpha-THDOC) is a neurosteroid, a gamma-aminobutyric acid (GABAA) modulator, which is used in the study of neurological disorders such as Alzheimer's disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name3α,21-Dihydroxy-5α-pregnan-20-one
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NoteResearch use only, not for human use.
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Brief Description3α,21-Dihydroxy-5α-pregnan-20-one (5alpha-THDOC) is a neurosteroid, a gamma-aminobutyric acid (GABAA) modulator, which is used in the study of neurological disorders such as Alzheimer's disease.
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Description3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorGABA Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number567-02-2
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Formula Weight334.49
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Molecular FormulaC21H34O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (298.96 mM; Ultrasonic )
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SMILES[H][C@@]12CC[C@H](C(=O)CO)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@H](O)CC[C@]12C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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alpha-Viniferin
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HA Peptide
Influenza Hemagglutinin (HA) Peptide is a tag peptide derived from an epitope of the influenza hemagglutinin protein.HA Peptide is a highly immunoreactive tag generally used for the separation of tagged proteins from cell culture supernatants and cell lysate under neutral pH conditions and thus are handy tools for coimmunoprecipitation but are also easily detected via western blot.
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Z-IETD-AFC
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