3α,21-Dihydroxy-5α-pregnan-20-one( —— )

Catalog No. M34145 CAS No. 567-02-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

3α,21-Dihydroxy-5α-pregnan-20-one
Note

Research use only, not for human use.
Brief Description

3α,21-Dihydroxy-5α-pregnan-20-one (5alpha-THDOC) is a neurosteroid, a gamma-aminobutyric acid (GABAA) modulator, which is used in the study of neurological disorders such as Alzheimer's disease.
Description

3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

GABA Receptor
Research Area

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Indication

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CAS Number

567-02-2
Formula Weight

334.49
Molecular Formula

C21H34O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (298.96 mM; Ultrasonic )
SMILES

[H][C@@]12CC[C@H](C(=O)CO)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@H](O)CC[C@]12C
Chemical Name

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