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SIRT6-IN-5
CAS No. 891002-11-2
SIRT6-IN-5( —— )
Catalog No. M34026 CAS No. 891002-11-2
SIRT6-IN-5（SIRT6 inhibitor 5） is a potent and selective SIRT6 inhibitor with an IC50 value of 34 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 78 | Get Quote |
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| 5MG | 116 | Get Quote |
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| 10MG | 187 | Get Quote |
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| 25MG | 365 | Get Quote |
|
| 50MG | 725 | Get Quote |
|
| 100MG | 963 | Get Quote |
|
| 500MG | 1917 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSIRT6-IN-5
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NoteResearch use only, not for human use.
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Brief DescriptionSIRT6-IN-5（SIRT6 inhibitor 5） is a potent and selective SIRT6 inhibitor with an IC50 value of 34 μM.
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DescriptionSIRT6-IN-2 (Compound 5) is a selective SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorSirtuin
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Research Area——
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Indication——
Chemical Information
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CAS Number891002-11-2
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Formula Weight366.32
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Molecular FormulaC19H14N2O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (170.62 mM; Ultrasonic )
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SMILESN(C(=O)C1=CC=C(NC(=O)C2=CC=CO2)C=C1)C3=CC(C(O)=O)=C(O)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Damonte P, et al. SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects. Bioorg Med Chem. 2017 Oct 15;25(20):5849-5858.?
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