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alphaSYN-IN-NAB2
CAS No. 1504588-00-4
alphaSYN-IN-NAB2( —— )
Catalog No. M33963 CAS No. 1504588-00-4
alphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 77 | In Stock |
|
| 5MG | 90 | In Stock |
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| 10MG | 149 | In Stock |
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| 25MG | 282 | In Stock |
|
| 50MG | 454 | In Stock |
|
| 100MG | 682 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1386 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamealphaSYN-IN-NAB2
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NoteResearch use only, not for human use.
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Brief DescriptionalphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity.
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DescriptionNAB2 is a neuron-protective agent. NAB2 strongly and selectively protects diverse cell types from α-syn toxicity. NAB2 promots endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4. NAB2 identifies a agentgable node in the biology of α-syn that can correct multiple aspects of its underlying pathology, including dysfunctional endosomal and endoplasmic reticulum-to-Golgi vesicle trafficking.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1504588-00-4
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Formula Weight389.88
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Molecular FormulaC23H20ClN3O
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1=C(N2C=3C(=CC(C(NCC4=C(Cl)C=CC=C4)=O)=CC3)N=C2)C=C(C)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tardiff DF, et al. Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. Science. 2013;342(6161):979-983. ?
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