alphaSYN-IN-NAB2

CAS No. 1504588-00-4

alphaSYN-IN-NAB2( —— )

Catalog No. M33963 CAS No. 1504588-00-4

alphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 70 Get Quote
5MG 90 Get Quote
10MG 149 Get Quote
25MG 273 Get Quote
50MG 449 Get Quote
100MG 660 Get Quote
500MG 1341 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    alphaSYN-IN-NAB2
  • Note
    Research use only, not for human use.
  • Brief Description
    alphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity.
  • Description
    NAB2 is a neuron-protective agent. NAB2 strongly and selectively protects diverse cell types from α-syn toxicity. NAB2 promots endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4. NAB2 identifies a agentgable node in the biology of α-syn that can correct multiple aspects of its underlying pathology, including dysfunctional endosomal and endoplasmic reticulum-to-Golgi vesicle trafficking.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1504588-00-4
  • Formula Weight
    389.88
  • Molecular Formula
    C23H20ClN3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=C(N2C=3C(=CC(C(NCC4=C(Cl)C=CC=C4)=O)=CC3)N=C2)C=C(C)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tardiff DF, et al. Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. Science. 2013;342(6161):979-983. ?
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