YE 120

CAS No. 383124-82-1

YE 120( —— )

Catalog No. M33950 CAS No. 383124-82-1

YE 120 is a highly potent GPR35 agonist (EC50: 32.5 nM) with potential anti-inflammatory and anti-cancer activities, which can be used to study G protein-coupled receptor-related diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 221 In Stock
10MG 328 In Stock
25MG 553 In Stock
50MG 774 In Stock
100MG 1070 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    YE 120
  • Note
    Research use only, not for human use.
  • Brief Description
    YE 120 is a highly potent GPR35 agonist (EC50: 32.5 nM) with potential anti-inflammatory and anti-cancer activities, which can be used to study G protein-coupled receptor-related diseases.
  • Description
    YE120 is a potent GPR35 agonist with an EC50 of 32.5 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    GPR
  • Recptor
    GPR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    383124-82-1
  • Formula Weight
    330.17
  • Molecular Formula
    C16H9Cl2N3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N#CC(C#N)=C1OC(C2=CC=C(Cl)C(Cl)=C2)(C(=C1C#N)C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Deng H, et al. Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists. J Med Chem. 2011 Oct 27;54(20):7385-96. ?
molnova catalog
related products
  • Questiomycin A

    Questiomycin A is an antibiotic produced in crème fraiche with antibacterial and anticancer activities. Questiomycin A suppresses expression of GRP78, a cell-protective ER chaperone protein.

  • DJ-V159

    DJ-V159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A).

  • BigLEN (rat)

    Potent GPR171 agonist (EC50 = 1.6 nM). ProSAAS-derived peptide. Regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells.