Linsidomine hydrochloride

CAS No. 16142-27-1

Linsidomine hydrochloride( —— )

Catalog No. M33929 CAS No. 16142-27-1

Linsidomine hydrochloride (SIN-1 chloride) is considered as a metabolite of moxidomine, with vasodilation, inhibition of platelet aggregation, and antiangina activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Linsidomine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Linsidomine hydrochloride (SIN-1 chloride) is considered as a metabolite of moxidomine, with vasodilation, inhibition of platelet aggregation, and antiangina activity.
  • Description
    SIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Drug Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    16142-27-1
  • Formula Weight
    206.63
  • Molecular Formula
    C6H11ClN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 50 mg/mL (241.98 mM; Ultrasonic)DMSO : 25 mg/mL (120.99 mM; Ultrasonic (<60°C)
  • SMILES
    Cl.NC1=CN(NO1)N1CCOCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nishikawa M,et al. Inhibition of platelet aggregation and stimulation of guanylate cyclase by an antianginal agent molsidomine and its metabolites. J Pharmacol Exp Ther. 1982 Jan;220(1):183-90. ?
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