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(E/Z)-SIB-1893
CAS No. 6266-99-5
(E/Z)-SIB-1893( —— )
Catalog No. M33927 CAS No. 6266-99-5
(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant activity .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 64 | In Stock |
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| 10MG | 112 | In Stock |
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| 25MG | 235 | In Stock |
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| 50MG | 365 | In Stock |
|
| 100MG | 551 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 1190 | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name(E/Z)-SIB-1893
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NoteResearch use only, not for human use.
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Brief Description(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant activity .
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Description(E/Z)-SIB-1893 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist.
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In Vitro——
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In Vivo(E)-SIB-1893 produces hypothermia in freely moving rats in a dose-dependent manner.
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Synonyms——
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PathwayNeuroscience
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TargetGluR
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RecptorGluR
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Research Area——
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Indication——
Chemical Information
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CAS Number6266-99-5
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Formula Weight195.26
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Molecular FormulaC14H13N
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (512.14 mM; Ultrasonic )
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SMILESC(=CC1=CC=CC=C1)C=2N=C(C)C=CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. ?uszczki JJ, et al. Non-competitive metabotropic glutamate subtype 5 receptor antagonist (SIB-1893) decreases body temperature in rats. Pharmacol Rep. 2005;57(6):795-801.?
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