Cart
sales@molnova.com
(E/Z)-SIB-1893
CAS No. 6266-99-5
(E/Z)-SIB-1893( —— )
Catalog No. M33927 CAS No. 6266-99-5
(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant activity .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 64 | In Stock |
|
| 10MG | 112 | In Stock |
|
| 25MG | 235 | In Stock |
|
| 50MG | 365 | In Stock |
|
| 100MG | 551 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1190 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name(E/Z)-SIB-1893
-
NoteResearch use only, not for human use.
-
Brief Description(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant activity .
-
Description(E/Z)-SIB-1893 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist.
-
In Vitro——
-
In Vivo(E)-SIB-1893 produces hypothermia in freely moving rats in a dose-dependent manner.
-
Synonyms——
-
PathwayNeuroscience
-
TargetGluR
-
RecptorGluR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number6266-99-5
-
Formula Weight195.26
-
Molecular FormulaC14H13N
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (512.14 mM; Ultrasonic )
-
SMILESC(=CC1=CC=CC=C1)C=2N=C(C)C=CC2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. ?uszczki JJ, et al. Non-competitive metabotropic glutamate subtype 5 receptor antagonist (SIB-1893) decreases body temperature in rats. Pharmacol Rep. 2005;57(6):795-801.?
molnova catalog
related products
-
(S)-MCPG
(S)-MCPG ((+)-MCPG) is a class I/II metabotropic glutamate receptors (mGluRs) antagonist that blocks spatial learning and long-term enhancement of the dentate gyrus in vivo in rats, and can be used to study neurological disorders.
-
MMPIP hydrochloride
MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system functions.
-
(RS)-3-Hydroxyphenyl...
(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.
