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Illudin S
CAS No. 1149-99-1
Illudin S( —— )
Catalog No. M33870 CAS No. 1149-99-1
Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 374 | In Stock |
|
| 10MG | 533 | In Stock |
|
| 25MG | 787 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameIlludin S
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NoteResearch use only, not for human use.
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Brief DescriptionIlludin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
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DescriptionIlludin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. Illudin S has genotoxic activities. Illudin S blocks the G1-S phase interface of the cell cycle in human leukemia cells.
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In VitroIlludin S (0-0.26 nM; 24-72 hours) shows cytotoxicity in human fibroblasts.Cell Viability Assay Cell Line:Human fibroblasts Concentration:0-0.26 nM Incubation Time:24 hours, 72 hours Result:Decreased cell survival.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorDNA Alkylator/Crosslinker | Apoptosis | Antifungal
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Research Area——
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Indication——
Chemical Information
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CAS Number1149-99-1
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Formula Weight264.32
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Molecular FormulaC15H20O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (189.16 mM; Ultrasonic )
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SMILESCC1=C2[C@@H](O)[C@](C)(CO)C=C2C(=O)[C@](C)(O)C11CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hansruedi Glatt, et al. Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells. Arch Toxicol . 2014 Jan;88(1):161-9.?
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