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Illudin S

CAS No. 1149-99-1

Illudin S( —— )

Catalog No. M33870 CAS No. 1149-99-1

Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Illudin S
  • Note
    Research use only, not for human use.
  • Brief Description
    Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
  • Description
    Illudin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. Illudin S has genotoxic activities. Illudin S blocks the G1-S phase interface of the cell cycle in human leukemia cells.
  • In Vitro
    Illudin S (0-0.26 nM; 24-72 hours) shows cytotoxicity in human fibroblasts.Cell Viability Assay Cell Line:Human fibroblasts Concentration:0-0.26 nM Incubation Time:24 hours, 72 hours Result:Decreased cell survival.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DNA Alkylator/Crosslinker | Apoptosis | Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1149-99-1
  • Formula Weight
    264.32
  • Molecular Formula
    C15H20O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (189.16 mM; Ultrasonic )
  • SMILES
    CC1=C2[C@@H](O)[C@](C)(CO)C=C2C(=O)[C@](C)(O)C11CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hansruedi Glatt, et al. Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells. Arch Toxicol . 2014 Jan;88(1):161-9.?
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