Cart
sales@molnova.com
Ansamitocin p-3 B
CAS No. 66584-72-3
Ansamitocin p-3 B( —— )
Catalog No. M33797 CAS No. 66584-72-3
Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
|
| 2MG | 30 | In Stock |
|
| 5MG | 48 | In Stock |
|
| 10MG | 77 | In Stock |
|
| 25MG | 130 | In Stock |
|
| 50MG | 184 | In Stock |
|
| 100MG | 305 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAnsamitocin p-3 B
-
NoteResearch use only, not for human use.
-
Brief DescriptionAnsamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
-
DescriptionAnsamitocin P-3 (Antibiotic C 15003P3) is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorMicrotubule Associated | ADC Cytotoxin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number66584-72-3
-
Formula Weight635.14
-
Molecular FormulaC32H43ClN2O9
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : ≥ 100 mg/mL (157.45 mM)
-
SMILES[H][C@@]12O[C@@]1(C)[C@H](CC(=O)N(C)c1cc(C\C(C)=C/C=C\[C@@H](OC)[C@@]3(O)C[C@]([H])(OC(=O)N3)[C@H]2C)cc(OC)c1Cl)OC(=O)C(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kiso T, et al. Screening for microtubule-disrupting antifungal agents by using a mitotic-arrest mutant of Aspergillus nidulans and novel action of phenylalanine derivatives accompanying tubulin loss. Antimicrob Agents Chemother. 2004 May;48(5):1739-48?
molnova catalog
related products
-
24-Dihydroxypyrimidi...
24-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme thymine 7-hydroxylase. It has been used to synthesize N1-alkylated uracil derivatives.
-
Pyrantel tartrate
Pyrantel tartrate is an antinematodal thiophene; and can elicit spastic muscle paralysis in parasitic worms due to prolonged activation of the excitatory nicotinic acetylcholine (nACh) receptors on body wall muscle.
-
Cyanidin-3-O-arabino...
Cyanidin-3-O-arabinoside chloride has antioxidant activity. It reduces the peroxynitrite-induced suppression of mitochondrial respiration, DNA damage, PARS activation and vascular dysfunction in HUVECs.
