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Alfuzosin

CAS No. 81403-80-7

Alfuzosin( —— )

Catalog No. M33794 CAS No. 81403-80-7

Alfuzosin (SL 77499) is an orally available, competitive α1-adrenoceptor antagonist.Alfuzosin induces smooth muscle relaxation in the bladder neck and prostate.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 38 Get Quote
25MG 68 Get Quote
50MG 113 Get Quote
100MG 177 Get Quote
500MG 446 Get Quote
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Biological Information

  • Product Name
    Alfuzosin
  • Note
    Research use only, not for human use.
  • Brief Description
    Alfuzosin (SL 77499) is an orally available, competitive α1-adrenoceptor antagonist.Alfuzosin induces smooth muscle relaxation in the bladder neck and prostate.
  • Description
    Alfuzosin (SL 77499-10) is an orally active, selective and competitive α1-adrenoceptor antagonist. Alfuzosin relaxes the muscles of the prostate and bladder neck, aiding in urination. Alfuzosin can be used in study of benign prostatic hyperplasia (BPH).
  • In Vitro
    ——
  • In Vivo
    Alfuzosin hydrochloride (10 mg/kg, p.o.; single) potently antagonizes phenylephrine-induced increases in urethral and arterial pressures up to 6 hours post dosing.Animal Model:Male Wistar rats (250-450 g).Dosage:10 mg/kg Administration:Oral administration; single.Result:Increased prostatic concentrations to 4.1-8.6 times higher than plasma concentration.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    81403-80-7
  • Formula Weight
    389.45
  • Molecular Formula
    C19H27N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 50 mg/mL (128.39 mM )
  • SMILES
    COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C1CCCO1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Martin DJ, et al. Relationship between the effects of alfuzosin on rat urethral and blood pressures and its tissue concentrations. Life Sci. 1998;63(3):169-76. ?
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