Cart
sales@molnova.com
ML352
CAS No. 1649450-12-3
ML352( —— )
Catalog No. M33756 CAS No. 1649450-12-3
ML352 is a selective and potent inhibitor of the presynaptic choline transporter (CHT), inhibits non-competitive choline uptake.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 49 | In Stock |
|
| 2MG | 29 | In Stock |
|
| 5MG | 44 | In Stock |
|
| 10MG | 74 | In Stock |
|
| 25MG | 159 | In Stock |
|
| 50MG | 254 | In Stock |
|
| 100MG | 365 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameML352
-
NoteResearch use only, not for human use.
-
Brief DescriptionML352 is a selective and potent inhibitor of the presynaptic choline transporter (CHT), inhibits non-competitive choline uptake.
-
DescriptionML352 is a noncompetitive inhibitor of the presynaptic choline transporter (CHT) with Ki values of 92 and 166 nM for HEK293 cells expressing human CHT and mouse forebrain synaptosomes, respectively.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetAChE
-
RecptorAChE
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1649450-12-3
-
Formula Weight387.47
-
Molecular FormulaC21H29N3O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (645.21 mM; Ultrasonic )
-
SMILESO=C(NCC=1ON=C(C1)C(C)C)C2=CC=C(OC)C(OC3CCN(C)CC3)=C2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ennis EA, Wright J, Retzlaff CL, McManus OB, Lin Z, Huang X, et al. Identification and characterization of ML352: a novel, noncompetitive inhibitor of the presynaptic choline transporter. ACS Chem Neurosci. 2015 Mar 18;6(3):417-27. ?
molnova catalog
related products
-
Acephate
Acephate is an anticholinesterase insecticide with a weak inhibitory effect on AChE in rats, but it can effectively inhibit AChE in cockroaches.
-
Rivastigmine
An acetylcholinesterase (AChE) inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
-
Zanapezil
Zanapezil (TAK-147) is a potent, selective acetylcholinesterase (AChE) inhibitor with IC50 of 97.7 nM.
