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MMP-2/MMP-9 Inhibitor I
CAS No. 193807-58-8
MMP-2/MMP-9 Inhibitor I( —— )
Catalog No. M33740 CAS No. 193807-58-8
MMP-2/MMP-9-IN-1 is a potent, highly selective, and orally bioavailable inhibitor of type IV collagenases [MMP-9 and MMP-2], exhibiting IC50 values of 0.24 μM for MMP-9 and 0.31 μM for MMP-2, which can be used to study cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 144 | In Stock |
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| 5MG | 122 | In Stock |
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| 10MG | 187 | In Stock |
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| 25MG | 376 | In Stock |
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| 50MG | 609 | In Stock |
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| 100MG | 918 | In Stock |
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| 200MG | 1237 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMMP-2/MMP-9 Inhibitor I
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NoteResearch use only, not for human use.
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Brief DescriptionMMP-2/MMP-9-IN-1 is a potent, highly selective, and orally bioavailable inhibitor of type IV collagenases [MMP-9 and MMP-2], exhibiting IC50 values of 0.24 μM for MMP-9 and 0.31 μM for MMP-2, which can be used to study cancer.
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DescriptionMMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and MMP-2) inhibitor with IC50s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetMMP
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RecptorMMP
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Research Area——
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Indication——
Chemical Information
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CAS Number193807-58-8
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Formula Weight381.44
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Molecular FormulaC21H19NO4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (131.08 mM; Ultrasonic )
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SMILESS(N[C@H](CC1=CC=CC=C1)C(O)=O)(=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Batimastat
Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3 with IC50 of 3 nM, 4 nM, 4 nM, 6 nM and 20 nM, respectively.
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Dehydroeffusol
Dehydroeffusol possesses anti-cancer, anxiolytic and sedative properties. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis.
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Epitheaflagallin 3-O...
Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts.
