Sphingosine-1-phosphate

CAS No. 26993-30-6

Sphingosine-1-phosphate( —— )

Catalog No. M33737 CAS No. 26993-30-6

Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, and GPR12. As an intracellular second messenger, it mobilizes Ca2+ and acts as an extracellular ligand for G-protein coupled receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 877 In Stock
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Biological Information

  • Product Name
    Sphingosine-1-phosphate
  • Note
    Research use only, not for human use.
  • Brief Description
    Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, and GPR12. As an intracellular second messenger, it mobilizes Ca2+ and acts as an extracellular ligand for G-protein coupled receptors.
  • Description
    Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors. Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite | S1P Receptor | LPL Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    26993-30-6
  • Formula Weight
    379.47
  • Molecular Formula
    C18H38NO5P
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?0.5 M NaOH : 3.8 mg/mL (10.01 mM; Ultrasonic (<60°C))DMSO : < 1 mg/mL (insoluble or slightly soluble)
  • SMILES
    [C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)(COP(=O)(O)O)N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Teresa Sanchez, et al. Structural and Functional Characteristics of S1P Receptors. J Cell Biochem. 2004 Aug 1;92(5):913-22.?
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