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Miriplatin hydrate
CAS No. 250159-48-9
Miriplatin hydrate( —— )
Catalog No. M33717 CAS No. 250159-48-9
Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | In Stock |
|
| 5MG | 56 | In Stock |
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| 10MG | 73 | In Stock |
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| 25MG | 141 | In Stock |
|
| 50MG | 211 | In Stock |
|
| 100MG | 306 | In Stock |
|
| 200MG | 440 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMiriplatin hydrate
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NoteResearch use only, not for human use.
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Brief DescriptionMiriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC).
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DescriptionMiriplatin hydrate (SM-11355 hydrate) is a chemotherapy agent which belongs to the class of alkylating agents.
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In VitroMiriplatin suspended in lipiodol (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.
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In VivoMiriplatin (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorDNA Alkylation
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Research Area——
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Indication——
Chemical Information
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CAS Number250159-48-9
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Formula Weight782.01
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Molecular FormulaC34H70N2O5Pt
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCC([O-])=O.N[C@H]1[C@H](N)CCCC1.O.[Pt+2]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23(3):344-8.?
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