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Ciglitazone
CAS No. 74772-77-3
Ciglitazone( —— )
Catalog No. M33630 CAS No. 74772-77-3
Ciglitazone (ADD 3878) is a potent and selective PPARγ agonist (EC50: 3 μM) and oral hypoglycemic agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 85 | In Stock |
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| 10MG | 125 | In Stock |
|
| 25MG | 208 | In Stock |
|
| 50MG | 300 | In Stock |
|
| 100MG | 445 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCiglitazone
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NoteResearch use only, not for human use.
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Brief DescriptionCiglitazone (ADD 3878) is a potent and selective PPARγ agonist (EC50: 3 μM) and oral hypoglycemic agent.
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DescriptionCiglitazone is a potent and selective PPARγ agonist (EC50=3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPPAR
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RecptorPPAR | Apoptosis | p38 MAPK
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Research Area——
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Indication——
Chemical Information
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CAS Number74772-77-3
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Formula Weight333.45
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Molecular FormulaC18H23NO3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (299.90 mM; Ultrasonic )
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SMILESCC1(COc2ccc(CC3SC(=O)NC3=O)cc2)CCCCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Willson TM, et al. The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem. 1996;39(3):665-668. ?
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