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Dasatinib carbaldehyde

CAS No. 2112837-79-1

Dasatinib carbaldehyde( —— )

Catalog No. M33555 CAS No. 2112837-79-1

Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 46 In Stock
25MG 84 In Stock
50MG 127 In Stock
100MG 183 In Stock
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Biological Information

  • Product Name
    Dasatinib carbaldehyde
  • Note
    Research use only, not for human use.
  • Brief Description
    Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER .
  • Description
    Dasatinib carbaldehyde (BMS-354825 carbaldehyde), the Dasatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER .
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Ligands for Target Protein for PROTAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2112837-79-1
  • Formula Weight
    471.96
  • Molecular Formula
    C21H22ClN7O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 33.33 mg/mL (70.62 mM; Ultrasonic )
  • SMILES
    N(C1=CC(N2CCN(C=O)CC2)=NC(C)=N1)C=3SC(C(NC4=C(C)C=CC=C4Cl)=O)=CN3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.?
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