Cart
sales@molnova.com
DSPE-PEG4-DBCO
CAS No. 2112738-14-2
DSPE-PEG4-DBCO( —— )
Catalog No. M33549 CAS No. 2112738-14-2
DSPE-PEG4-DBCO is a PEG-based linker for PROTACs that joins two essential ligands, essential for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 73 | In Stock |
|
| 10MG | 117 | In Stock |
|
| 25MG | 235 | In Stock |
|
| 50MG | 368 | In Stock |
|
| 100MG | 550 | In Stock |
|
| 200MG | 797 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDSPE-PEG4-DBCO
-
NoteResearch use only, not for human use.
-
Brief DescriptionDSPE-PEG4-DBCO is a PEG-based linker for PROTACs that joins two essential ligands, essential for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
-
DescriptionDSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DSPE-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorPROTACs
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2112738-14-2
-
Formula Weight1282.67
-
Molecular FormulaC71H116N3O15P
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(CCNC(CCOCCOCCOCCOCCC(NCCOP(OC[C@H](OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(=O)O)=O)=O)(=O)N1C=2C(C#CC=3C(C1)=CC=CC3)=CC=CC2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
D-(+)-Malic acid
D-Malic acid is a dicarboxylic acid that is made by all living organisms. Malic acid has two stereoisomeric forms (L- and D-enantiomers). The malate anion is an intermediate in the citric acid cycle.
-
Hydroxocobalamin
Hydroxocobalamin (Standard) is the analytical standard of Hydroxocobalamin. This product is intended for research and analytical applications. Hydroxocobalamin (Vitamin B12a) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia.
-
1-Hydroxy-2,3,4,7-te...
1-Hydroxy-2,3,4,7-tetramethoxy-xanthone has vasodilatory action, it can cause vasodilation in the coronary artery pre-contracted with 1uM 5-hydroxytryptamine (5-HT), with the EC 50 value of 6.6±1.4 uM.
