Cart
sales@molnova.com
MRE3008F20
CAS No. 252979-43-4
MRE3008F20( —— )
Catalog No. M33435 CAS No. 252979-43-4
MRE3008F20 is a species-selective and potent adenosine A3 receptor (AA3R) antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used in glaucoma and asthma studies.CAS 13483-88-88-9
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 88 | In Stock |
|
| 5MG | 147 | In Stock |
|
| 10MG | 217 | In Stock |
|
| 25MG | 369 | In Stock |
|
| 50MG | 528 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMRE3008F20
-
NoteResearch use only, not for human use.
-
Brief DescriptionMRE3008F20 is a species-selective and potent adenosine A3 receptor (AA3R) antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used in glaucoma and asthma studies.CAS 13483-88-88-9
-
DescriptionMRE3008F20 is a highly efficient, highly selective and radioactive adenosine A3 receptor (AA3R) antagonist (Ki=1.8 nM). MRE3008F20 effectively antagonises Cl-IB-MECA-induced cAMP production in resting lymphocytes with an IC50 value of 5 nM. MRE3008F20 can be used in the study of AA3R.
-
In VitroMRE3008F20 (0.1-100 nM) antagonizes 100 nM Cl-IB-MECA-induced inhibition of cAMP levels in resting human lymphocytes.Cell Viability Assay Cell Line:Human lymphocytes Concentration:0.1-100 nM Incubation Time: Result:Antagonized 100 nM Cl-IB-MECA-induced inhibition of cAMP levels with an IC50 of 5.0 nM in resting Lymphocytes.
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetAdenosine Receptor
-
RecptorAdenosine Receptor | cAMP
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number252979-43-4
-
Formula Weight432.44
-
Molecular FormulaC21H20N8O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(NC1=CC=C(OC)C=C1)NC2=NC3=NN(C=C3C4=NC(=NN24)C=5OC=CC5)CCC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Gessi S, et al. Expression of A3 adenosine receptors in human lymphocytes: up-regulation in T cell activation. Mol Pharmacol. 2004 Mar;65(3):711-9.?
molnova catalog
related products
-
Evodenoson
Evodenoson (ATL313) is a potent and selective adenosine A2a receptor (A2aR) agonist for the treatment of eye diseases, tumors, and immune system disorders, and may be used in studies of open-angle glaucoma and blood tumors.
-
LUF6096
LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically while demonstrating low orthosteric affinity across adenosine receptors.
-
GW-493838
GW-493838 is a potent adenosine A1A receptor agonist for the treatment of dyslipidemia and neuropathic pain, with analgesic effects on post-herpetic neuralgia or peripheral nerve damage caused by trauma or surgery.
