Managlinat dialanetil

CAS No. 280782-97-0

Managlinat dialanetil( —— )

Catalog No. M33426 CAS No. 280782-97-0

Managlinat dialanetil (MB06322) is an orally available and potent fructose 1,6-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of type 2 diabetes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 354 Get Quote
5MG 549 Get Quote
10MG 873 Get Quote
25MG 1270 Get Quote
50MG 1711 Get Quote
100MG 2241 Get Quote
500MG 4437 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Managlinat dialanetil
  • Note
    Research use only, not for human use.
  • Brief Description
    Managlinat dialanetil (MB06322) is an orally available and potent fructose 1,6-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of type 2 diabetes.
  • Description
    Managlinat dialanetil (MB06322) is an orally bioavailable inhibitor of fructose 1,6-bisphosphatase (FBPase) for the treatment of type 2 diabetes .
  • In Vitro
    ——
  • In Vivo
    Managlinat dialanetil dose-dependently inhibits GNG as well as lower basal and postprandial blood glucose levels in Zucker diabetic fatty (ZDF) rats after oral administration.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Phosphatase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    280782-97-0
  • Formula Weight
    500.55
  • Molecular Formula
    C21H33N4O6PS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (49.95 mM; Ultrasonic )
  • SMILES
    C(C(C)C)C1=C(N=C(N)S1)C=2OC(P(N[C@H](C(OCC)=O)C)(N[C@H](C(OCC)=O)C)=O)=CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang Y, et al. Managlinat dialanetil, a fructose-1,6-bisphosphatase inhibitor for the treatment of type 2 diabetes. Curr Opin Investig Drugs. 2007 Oct;8(10):849-58.?
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