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Managlinat dialanetil
CAS No. 280782-97-0
Managlinat dialanetil( —— )
Catalog No. M33426 CAS No. 280782-97-0
Managlinat dialanetil (MB06322) is an orally available and potent fructose 1,6-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of type 2 diabetes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 330 | In Stock |
|
| 10MG | 523 | In Stock |
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| 25MG | 787 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameManaglinat dialanetil
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NoteResearch use only, not for human use.
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Brief DescriptionManaglinat dialanetil (MB06322) is an orally available and potent fructose 1,6-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of type 2 diabetes.
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DescriptionManaglinat dialanetil (MB06322) is an orally bioavailable inhibitor of fructose 1,6-bisphosphatase (FBPase) for the treatment of type 2 diabetes .
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In Vitro——
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In VivoManaglinat dialanetil dose-dependently inhibits GNG as well as lower basal and postprandial blood glucose levels in Zucker diabetic fatty (ZDF) rats after oral administration.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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RecptorPhosphatase
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Research Area——
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Indication——
Chemical Information
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CAS Number280782-97-0
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Formula Weight500.55
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Molecular FormulaC21H33N4O6PS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (49.95 mM; Ultrasonic )
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SMILESC(C(C)C)C1=C(N=C(N)S1)C=2OC(P(N[C@H](C(OCC)=O)C)(N[C@H](C(OCC)=O)C)=O)=CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wang Y, et al. Managlinat dialanetil, a fructose-1,6-bisphosphatase inhibitor for the treatment of type 2 diabetes. Curr Opin Investig Drugs. 2007 Oct;8(10):849-58.?
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