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Fmoc-NH-PEG8-CH2CH2COOH
Fmoc-NH-PEG8-CH2CH2COOH
CAS No. 756526-02-0
Fmoc-NH-PEG8-CH2CH2COOH( —— )
Catalog No. M33361 CAS No. 756526-02-0
Fmoc-NH-PEG8-CH2CH2COOH is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) for forming antibody-drug conjugates .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 28 | In Stock |
|
| 100MG | 37 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 120 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFmoc-NH-PEG8-CH2CH2COOH
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NoteResearch use only, not for human use.
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Brief DescriptionFmoc-NH-PEG8-CH2CH2COOH is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) for forming antibody-drug conjugates .
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DescriptionFmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayAntibody Drug Conjugates (ADC)
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TargetADCs Linker/Click Chemistry
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RecptorADC Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number756526-02-0
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Formula Weight663.75
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Molecular FormulaC34H49NO12
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Purity>98% (HPLC)
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Solubility——
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SMILESC(OC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem. 2019 Dec 28;17(48):10237-10244.?
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