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Estetrol
CAS No. 15183-37-6
Estetrol( —— )
Catalog No. M33354 CAS No. 15183-37-6
Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
|
| 5MG | 77 | In Stock |
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| 10MG | 132 | In Stock |
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| 25MG | 282 | In Stock |
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| 50MG | 477 | In Stock |
|
| 100MG | 799 | In Stock |
|
| 200MG | 1079 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEstetrol
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NoteResearch use only, not for human use.
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Brief DescriptionEstetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.
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DescriptionEstetrol, a natural estrogen synthesized exclusively during pregnancy by the human fetal liver, is a selective nuclear estrogen receptor modulator. Estetrol exerts estrogenic actions on the endometrium or the central nervous system but presents antagonistic effects on the breast.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorEndogenous Metabolite | Estrogen Receptor/ERR
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Research Area——
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Indication——
Chemical Information
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CAS Number15183-37-6
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Formula Weight304.38
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Molecular FormulaC18H24O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (328.54 mM; Ultrasonic )
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SMILESC[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])([C@@H](O)[C@@H](O)[C@@H]2O)[H]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Valéra MC, et al. Effect of estetrol, a selective nuclear estrogen receptor modulator, in mouse models of arterial and venous thrombosis. Mol Cell Endocrinol. 2018 Dec 5;477:132-139.?
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