BS3 Crosslinker

CAS No. 82436-77-9

BS3 Crosslinker( —— )

Catalog No. M33298 CAS No. 82436-77-9

BS3 Crosslinker is a non-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It connects antibodies with drugs, thereby enhancing the overall efficiency and effectiveness of the resulting ADC.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 In Stock
10MG 46 In Stock
25MG 93 In Stock
50MG 142 In Stock
100MG 207 In Stock
200MG 300 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BS3 Crosslinker
  • Note
    Research use only, not for human use.
  • Brief Description
    BS3 Crosslinker is a non-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It connects antibodies with drugs, thereby enhancing the overall efficiency and effectiveness of the resulting ADC.
  • Description
    BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • In Vitro
    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    82436-77-9
  • Formula Weight
    528.47
  • Molecular Formula
    C16H20N2O14S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (189.23 mM; Ultrasonic)
  • SMILES
    O=C(ON1C(=O)CC(C1=O)S(=O)(=O)O)CCCCCCC(=O)ON2C(=O)CC(C2=O)S(=O)(=O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.?
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