BS3 Crosslinker

CAS No. 82436-77-9

BS3 Crosslinker( —— )

Catalog No. M33298 CAS No. 82436-77-9

BS3 Crosslinker is a non-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It connects antibodies with drugs, thereby enhancing the overall efficiency and effectiveness of the resulting ADC.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BS3 Crosslinker
  • Note
    Research use only, not for human use.
  • Brief Description
    BS3 Crosslinker is a non-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It connects antibodies with drugs, thereby enhancing the overall efficiency and effectiveness of the resulting ADC.
  • Description
    BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • In Vitro
    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    82436-77-9
  • Formula Weight
    528.47
  • Molecular Formula
    C16H20N2O14S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (189.23 mM; Ultrasonic)
  • SMILES
    O=C(ON1C(=O)CC(C1=O)S(=O)(=O)O)CCCCCCC(=O)ON2C(=O)CC(C2=O)S(=O)(=O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.?
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