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Ascamycin
CAS No. 91432-48-3
Ascamycin( —— )
Catalog No. M33271 CAS No. 91432-48-3
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 747 | In Stock |
|
| 5MG | 787 | In Stock |
|
| 10MG | 1074 | In Stock |
|
| 25MG | 1511 | In Stock |
|
| 50MG | 1841 | In Stock |
|
| 100MG | 2325 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 4557 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAscamycin
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NoteResearch use only, not for human use.
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Brief DescriptionAscamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp.
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DescriptionAscamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against Xanthomonas species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei, respectively.
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In VitroThe Ascamycin has C2-chloroadenine as the base on C-1' which lacks the chlorine. Ascamycin has a selective antibacterial activity against Xanthomonas species. When Ascamycin is dealanylated, Dealanylascamycin shows a broad antibacterial activity against various Gram-negative and Gram-positive bacteria. Xanthomonas citri is susceptible to Ascamycin by virtue of the Ascamycin-dealanylating enzyme on the cell surface.
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetAntibiotic
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RecptorNucleoside Antimetabolite/Analog | Antibacterial | Antibiotic
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Research Area——
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Indication——
Chemical Information
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CAS Number91432-48-3
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Formula Weight451.84
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Molecular FormulaC13H18ClN7O7S
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Purity>98% (HPLC)
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Solubility——
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SMILESNC1=C2C(N(C=N2)[C@@H]3O[C@H](COS(NC([C@H](C)N)=O)(=O)=O)[C@@H](O)[C@H]3O)=NC(Cl)=N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Isono K, et al. Ascamycin and dealanylascamycin, nucleoside antibiotics from Streptomyces sp. J Antibiot (Tokyo). 1984 Jun;37(6):670-2.?
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