4-Azido-L-phenylalanine

Research use only, not for human use.

4-Azido-L-phenylalanine (p-Azido-L-phenylalanine) is an amino acid derivative that acts as a photoaffinity marker and can be used to detect localized protein environments.

4-Azido-L-phenylalanine is an unnatural amino acid, which is used as an effective vibrational reporter of local protein environments. 4-Azido-L-phenylalanine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

In cell-free protein synthesis (CFPS) method, 0.9-1.7 mg/mL of modified soluble super-folder green fluorescent protein (sfGFP) containing either 4-Azido-L-phenylalanine or p-propargyloxy-l-phenylalanine (pPaF) accumulate in the CFPS solutions.

——

——

Others

Other Targets

Others

——

——

33173-53-4

206.2

C9H10N4O2

>98% (HPLC)

In Vitro:?H2O : 25 mg/mL (121.24 mM; ultrasonic and adjust pH to 11 with NaOH)DMSO : 5 mg/mL (24.25 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 80°C )

N[C@@H](CC1=CC=C(C=C1)N=[N+]=[N-])C(O)=O

——

(-20℃)

With Ice Pack

≥ 2 years