RO5263397
CAS No. 1357266-05-7
RO5263397( —— )
Catalog No. M33107 CAS No. 1357266-05-7
RO5263397 is a TAAR1 specific agonist with oral activity that has been used in antidepressant studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 75 | In Stock |
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| 5MG | 68 | In Stock |
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| 10MG | 122 | In Stock |
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| 25MG | 274 | In Stock |
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| 50MG | 400 | In Stock |
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| 100MG | 578 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRO5263397
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NoteResearch use only, not for human use.
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Brief DescriptionRO5263397 is a TAAR1 specific agonist with oral activity that has been used in antidepressant studies.
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DescriptionRO5263397 is a potent, selective, and orally available TAAR1 agonist, with EC50s of 17 and 35 nM for human TAAR1 and rat TAAR1, respectively. RO5263397 regulates wakefulness and EEG spectral composition. Antidepressant-like effect.
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In Vitro——
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In VivoAnimal Model:Adult 4-5-month-old male WT littermates (C57BL/6 background) Dosage:0.1, 0.3, 1?mg/kg Administration:p.o.; dosing at the mid-light phase (ZT6)?Result:Increased wake time at 0.3 and 1?mg/kg
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1357266-05-7
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Formula Weight194.21
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Molecular FormulaC10H11FN2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 260 mg/mL (1338.76 mM; Ultrasonic )
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SMILESCc1c(F)cccc1[C@H]1COC(N)=N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Anthrone
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2-Hydroxy-3-methylbu...
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Echinocystic acid 28...
Echinocystic acid 28-O-β-D-glucoside is a metabolite resulting from the microbial oxidation and glucosidation of Echinocystic acid.
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