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MRS1845
CAS No. 544478-19-5
MRS1845( —— )
Catalog No. M33033 CAS No. 544478-19-5
MRS1845 is an ORAI1 inhibitor and calcium entry (SOCE) blocker that blocks VP-induced SOCE, OS, and Ca(2+) deposition.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 73 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMRS1845
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NoteResearch use only, not for human use.
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Brief DescriptionMRS1845 is an ORAI1 inhibitor and calcium entry (SOCE) blocker that blocks VP-induced SOCE, OS, and Ca(2+) deposition.
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DescriptionMRS1845 is a selective store-operated calcium (SOC) channel inhibitor with an IC50 of 1.7 μM. MRS1845 is an ORAI1 inhibitor. MRS1845 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number544478-19-5
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Formula Weight398.41
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Molecular FormulaC21H22N2O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 83.33 mg/mL (209.16 mM )
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SMILESCCOC(=O)C1=C(C)N(CC#C)C(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Harper JL, et al. Dihydropyridines as inhibitors of capacitative calcium entry in leukemic HL-60 cells. Biochem Pharmacol. 2003 Feb 1;65(3):329-38.?
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