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MethADP

CAS No. 3768-14-7

MethADP( —— )

Catalog No. M33017 CAS No. 3768-14-7

MethADP (Adenosine 5'-(α,β-methylene)diphosphate) is a specific CD73 inhibitor that inhibits the enzyme ecto-5′-nucleotidase (ecto), which has been used in the study of neurological and cardiovascular diseases.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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5MG	471	In Stock
10MG	658	In Stock
25MG	1017	In Stock
50MG	1349	In Stock
100MG	1823	In Stock
200MG	Get Quote	In Stock
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Biological Information

Product Name

MethADP
Note

Research use only, not for human use.
Brief Description

MethADP (Adenosine 5'-(α,β-methylene)diphosphate) is a specific CD73 inhibitor that inhibits the enzyme ecto-5′-nucleotidase (ecto), which has been used in the study of neurological and cardiovascular diseases.
Description

MethADP is a specific CD73 inhibitor.
In Vitro

MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation.
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

CD73
Research Area

——
Indication

——

Chemical Information

CAS Number

3768-14-7
Formula Weight

425.23
Molecular Formula

C11H17N5O9P2
Purity

>98% (HPLC)
Solubility

——
SMILES

O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(CP(=O)(O)O)(=O)O)[C@H]1O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Mohlin C, et al. Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells. Pharmacology. 2009;84(4):196-202.?

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