Fumarate hydratase-IN-1

CAS No. 1644060-37-6

Fumarate hydratase-IN-1( —— )

Catalog No. M32930 CAS No. 1644060-37-6

Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 65 In Stock
2MG 29 In Stock
5MG 57 In Stock
10MG 93 In Stock
25MG 182 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Fumarate hydratase-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity.
  • Description
    Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Mitochondrial Metabolism
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1644060-37-6
  • Formula Weight
    446.54
  • Molecular Formula
    C27H30N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (111.97 mM; Ultrasonic )
  • SMILES
    CCOC(=O)[C@@]12CCCC=C1N(Cc1ccc(cc1)-c1ccccc1)C(=O)[C@H]2CC(=O)NC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Takeuchi T et al. Identification of Fumarate Hydratase Inhibitors with Nutrient-Dependent Cytotoxicity. J Am Chem Soc, 2015 Jan 21, 137(2): 564-567.?
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