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CRTh2 antagonist 2
CAS No. 780763-95-3
CRTh2 antagonist 2( —— )
Catalog No. M32868 CAS No. 780763-95-3
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 115 | In Stock |
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| 5MG | 86 | In Stock |
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| 10MG | 141 | In Stock |
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| 25MG | 224 | In Stock |
|
| 50MG | 300 | In Stock |
|
| 100MG | 384 | In Stock |
|
| 200MG | 510 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCRTh2 antagonist 2
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NoteResearch use only, not for human use.
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Brief DescriptionCRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
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DescriptionCRTh2 antagonist 2 is selective and potent CRTH2 antagonist extracted from patent US20140148470A1, compound Example 1, has an IC50 of ≤10 nM. CRTh2 antagonist 2 can be used in research of androgenic alopecia.
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In VitroCRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells) protein, also known as GPR44, is a G-protein coupled receptor (GPCR) which is amongst other ligands most strongly activated by prostaglandin D2 (PGD2). PGD2 is a product of prostaglandin D2 synthase (PTGDS).
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetGPR
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RecptorGPR
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Research Area——
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Indication——
Chemical Information
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CAS Number780763-95-3
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Formula Weight474.94
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Molecular FormulaC26H23ClN4O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (263.19 mM; Ultrasonic )
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SMILESCN(C)c1nc(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)nc(Cl)c1CC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Andreas Schnapp, et al. Pyrimidine compounds for treating hairloss. US20140148470A1.
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