Bucindolol( —— )

Catalog No. M32820 CAS No. 71119-11-4

Bucindolol (BMY 13105) is a novel and potent β1-adrenergic receptor blocker that mediates vasodilation and can be used to study chronic heart failure.

Purity : >98% (HPLC)

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Biological Information

Product Name

Bucindolol
Note

Research use only, not for human use.
Brief Description

Bucindolol (BMY 13105) is a novel and potent β1-adrenergic receptor blocker that mediates vasodilation and can be used to study chronic heart failure.
Description

Bucindolol is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Adrenergic Receptor
Recptor

Adrenergic Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

71119-11-4
Formula Weight

363.45
Molecular Formula

C22H25N3O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (275.14 mM; Ultrasonic )
SMILES

CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1ccccc1C#N
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Liggett SB, et al. A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11288-93.?

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