BuChE-IN-TM-10

CAS No. 2313524-95-5

BuChE-IN-TM-10( —— )

Catalog No. M32819 CAS No. 2313524-95-5

BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE) with an IC50 of 8.9 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 278 In Stock
5MG 426 In Stock
10MG 625 In Stock
25MG 938 In Stock
50MG 1283 In Stock
100MG 1758 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BuChE-IN-TM-10
  • Note
    Research use only, not for human use.
  • Brief Description
    BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE) with an IC50 of 8.9 nM.
  • Description
    BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    AChR
  • Recptor
    AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2313524-95-5
  • Formula Weight
    498.66
  • Molecular Formula
    C32H38N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(/C=C/C1=CC(OC)=C(OCCCCN(CC2=CC=CC=C2)CC)C=C1)(=O)N3CC=4C(CC3)=CC=CC4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sang Z, et al. Design, Synthesis, and Evaluation of Novel Ferulic Acid Derivatives as Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease. ACS Chem Neurosci. 2019 Feb 20;10(2):1008-1024.?
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